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Effectiveness of Iron Amino Acid Chelate on the Treatment of Iron Deficiency Anaemia in Adolescents

Pineda O, Ashmead HD, Perez JM, and Lemus CP
Journal of Applied Nutrition, Volume 46, Numbers 1 & 2

In this study, the tolerability of supplemental iron in the chelated form of Albion’s Ferrochel® was compared to ferrous sulfate in a randomized, double-blind, cross-over trial. Of the 38 women evaluated, 37% experienced moderate-to-severe side-effects with symptoms of bloating, constipation, and nausea while taking the sulfate formulation. However, only 21% of participants experienced some of these symptoms while taking the chelate formulation. The remaining study participants had the same symptom profile with both preparations. A significant number of women preferred the chelate to the sulfate formulation because of the lower number of side effects experienced with the Albion chelate.